Cancer Clinical Trials for Pediatrics
Research projects by attending physicians affiliated with Inova Comprehensive Cancer and Research Institute
Last updated August 2012
This list of open research trials is meant to be a general information resource only. It should not replace information given by the patient's physician. These studies may close without warning.
In addition to the consent forms for these studies, additional general disease
information can be found on www.cancer.gov.
Learn more about clinical trials for patients at Inova 
Other online resources with helpful information on clinical trials:
Contact us
For information on any pediatric study, contact:
Keary Jane’t, Study Coordinator
703-576-7279
Marshal Schorin, MD
Inova Fairfax Hospital for Children
3300 Gallows Road
Falls Church, VA 22042
Disease: Pediatric Bone Tumors
| Study # |
Study Title |
Status |
| AOST0331 |
EURAMOS 1: Randomized Trial of the European and American Osteosarcoma Study Group to Optimize Treatment Strategies and Resectable Osteosarcoma Based On Histological Response to Pre-Operative Chemotherapy **NCI DRUG Pegylated Interferon alfa 2b |
Open |
| AEWS0331 |
European Ewing Tumor Working Initiative of National Groups, Ewing Tumor Studies 1999 – Metastatic Pulmonary ONLY |
Open |
| AOST06B1 |
A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Based on Histological Response to Pre-Operative Chemotherapy |
Open |
Disease: Pediatric Brain Tumors
| Study # |
Study Title |
Status |
| ACNS02B3 |
A COG Protocol for Collecting and Banking Pediatric Brain Tumors – ALL Tumors |
Open |
| ACNS0331 |
A Study Evaluation Limited Target Volume Boost Irradiation and Reduced Dose Crainospinal Radiotherapy and Chemotherapy with Newly Diagnosed Standard Risk Medulloblastoma |
Open |
| ACNS0332 |
Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients |
Open |
| ACNS0334 |
A Phase III, Randomized Trial for the Treatment of Newly Diagnosed Supratentorial PNET and High-Risk Medulloblastoma in Children <36 Months Old with Intensive Induction Chemotherapy with Methotrexate Followed by Consolidation with Stem Cell Rescue versus the Same Therapy without Methofrexate |
Open |
Disease: Pediatric Leukemia
| Study # |
Study Title |
Status |
| AALL03N1 |
Understanding the Role of Adherence in the Ethnic Differences in Survival After Childhood Acute Lymphoblastic Leukemia |
Open |
| AALL03B1 |
Classification of Acute Lympoblastic Leukemia |
Open |
| AALL0932 |
Treatment for Patients with Newly Diagnosed Standard Risk B=Precursor Acute Lymphoblastic Leukemia |
Open |
| AALL0434 |
Intensified Methotrexate, Nelarabine (Compound 506U78; IND #52611) and Augmented BFM Therapy for Children and Young Adults with Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia |
Open |
| AALL0631 |
A Phase III Study of Risk Directed Therapy for Infants with Acute Lymphoblastic Leukemia: Randomization of Highest Risk Infants Intensive Chemotherapy +/- FLT3 Inhibition (CEP-701, Lestaurtinib; IND#76431; NSC#617807) |
Open |
| AAML1031 |
A Phase III Randomized Trial for Patients with de novo AML using Bortezomib and Sorafenib (IND#114480; NSC# 681239, NSC# 724772) for Patients with High Allelic Ratio FLT3/ITD |
Open |
| ACCL0933 |
A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML) |
Open |
| AAML08B1 |
Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome (DS) |
Open |
Disease: Pediatric Nasopharyngeal
| Study # |
Study Title |
Status |
| ARAR0331 |
Treatment of Childhood Nasopharyngeal Carcinoma |
Open |
Disease: Pediatric Neuroblastoma
| Study # |
Study Title |
Status |
| ANBL00B1 |
Neuroblastoma Biology Protocol |
Open |
| ANBL0532 |
Phase III Randomized Trial Single vs. Tandem Myeloablative Consolidation Therapy for High Risk Neuroblastoma |
Open |
| ANBL0032 |
Phase III Chimeric Anti-Body in High Risk NBL |
Open |
Disease: Pediatric Rare Tumors
| Study # |
Study Title |
Status |
| ABTR01B1 |
A COG Protocol for Collecting and Banking Pediatric Rare Tumors |
Open |
Disease: Pediatric Renal Tumors
| Study # |
Study Title |
Status |
| ARST0321 |
Treatment for High Risk Renal Tumors |
Open |
Disease: Pediatric Soft Tissue Sarcoma
| Study # |
Study Title |
Status |
| ARST0921 |
A Randomized Phase II Trial of Bevacizumab (IND# 7921, Avastin) and Temsirolimus (IND# 61010, Torisel) in Combination with Intravenous Vinorelbine and Cyclophosphamide in Patients with Recurrent/Refractory Rhabdomyosarcoma |
Open |
| D9902 |
A COG Protocol for Collecting and Banking Soft Tissue Sarcoma Specimens **To enroll in front-line therapeutic study, all subjects must first be registered on this study |
Open |
| ARST0321 |
Phase II Study of Sulindac and Tamoxifen in Patients with Desmoid Tumors that are Recurrent or Not Amendable to Standard Therapy |
Open |
| ARST0331 |
Vincristine, Dactinomycin, and Lower Doses of Cyclophosphamide with or without Radiation Therapy for Patients with Newly Diagnosed Low Risk Embryonal/Botryoid/Spindle Cell Rhabdomyosarcoma |
Open |
| ARST0531 |
A Randomized Study of Vincristine, Dactinomycin and Cyclophosphamide (VAC) vs. (VAC) Alternating with Vincristine and Irinotecan for Patients with Intermediate Risk Rhabdomyosarcoma |
Open |
| ARST0332 |
Risk-Based Treatment for Non Rhabdo Soft Tissue Sarcomas |
Open |
Disease: Pediatric Wilms
| AREN0321 |
Treatment of High Risk Tumors |
Status |
| AREN03B2 |
Renal Tumors Classification, Biology and Banking Study |
Open |
| AREN0533 |
Treatment of Newly Dx’d Higher Risk Favorable Histology Wilms Tumor |
Open |
| AREN0532 |
Treatment for Very Low, Low and Standard Risk Favorable Histology Wilms Tumor |
Open |
Disease: Late Effects and Registry
| Study # |
Study Title |
Status |
| ATLE03N1 |
Late Effects |
Open |
| ACCLO5C1 |
A Group-Wide Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy |
Open |
| ACCRNO7 |
Protocol for Enrollment on the Official COG Registry, The Childhood Cancer Research Network (CCRN) |
Open |
| ALTE05N1 |
Umbrella Long-term Follow-up Protocol |
Open |
