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Cancer Clinical Trials for Pediatrics

Research projects by attending physicians affiliated with Inova Comprehensive Cancer and Research Institute

Last updated June 2014

This list of open research trials is meant to be a general information resource only. It should not replace information given by the patient's physician. These studies may close without warning. In addition to the consent forms for these studies, additional general disease
information can be found on

Learn more about clinical trials for patients at Inova arrow

Other online resources with helpful information on clinical trials:

Contact us

For information on any pediatric study, contact:
Keary Jane’t, Study Coordinator

Marshal Schorin, MD
Inova Children's Hospital
3300 Gallows Road
Falls Church, VA  22042

Pediatric Bone Tumors

Study # Study Title Status
AOST06B1 A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Based on Histological Response to Pre-Operative Chemotherapy Open
AEWS1031 A Phase III Radomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-metastatic Ewing Sarcoma Open

Pediatric Brain Tumors

Study # Study Title Status
ACNS02B3 A COG Protocol for Collecting and Banking Pediatric Brain Tumors – ALL TUMORS Open
 ACNS0332 Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients  Open
ACNS0334 A Phase III, Randomized Trial for the Treatment of Newly Diagnosed Supratentorial PNET and High-Risk Medulloblastoma in Children <36 Months Old with Intensive Induction Chemotherapy with Methotrexate Followed by Consolidation with Stem Cell Rescue versus the Same Therapy without Methofrexate Open
ACNS0831 A Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 Years Open

Pediatric Leukemia

Study # Study Title Status
AALL08B1 Classification of Acute Lympoblastic Leukemia Open
AALL0932 Treatment for Patients with Newly Diagnosed Standard Risk B=Precursor Acute Lymphoblastic Leukemia Open
AALL0434 Intensified Methotrexate, Nelarabine (Compound 506U78; IND #52611) and Augmented BFM Therapy for Children and Young Adults with Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia Open
AALL0631 A Phase III Study of Risk Directed Therapy for Infants with Acute Lymphoblastic Leukemia: Randomization of Highest Risk Infants Intensive Chemotherapy +/- FLT3 Inhibition (CEP-701, Lestaurtinib; IND#76431; NSC#617807) Open
AAML1031 A Phase III Randomized Trial for Patients with de novo AML using Bortezomib and Sorafenib (IND#114480; NSC# 681239, NSC# 724772) for Patients with High Allelic Ratio FLT3/ITD Open
ACCL0933 A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML) Open
AAML08B1 Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome (DS) Open
AALL1131 A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND#73789, NSC#606869) in the Very High Risk Stratum Open

Pediatric Neuroblastoma

Study # Study Title Status
ANBL00B1 Neuroblastoma Biology Protocol Open
ANBL0032 Phase III Chimeric Anti-Body in High Risk NBL Open

Pediatric Rare Tumors

Study # Study Title Status
ABTR01B1 A COG Protocol for Collecting and Banking Pediatric Rare Tumors Open

Pediatric Soft Tissue Sarcoma

Study # Study Title Status
D9902 A COG Protocol for Collecting and Banking Soft Tissue Sarcoma Specimens **To enroll in front-line therapeutic study, all subjects must first be registered on this study Open

Pediatric Wilms

Study # Study Title Status
AREN03B2 Renal Tumors Classification, Biology and Banking Study Open

Pediatric Hepatoblastoma

Study # Study Title Status
AHEP0731 Treatment of Children with All Stages of Hepatoblastoma Open

Late Effects and Registry

Study # Study Title Status
ATLE03N1 Late Effects Open
ACCRNO7 Protocol for Enrollment on the Official COG Registry, The Childhood Cancer Research Network (CCRN) Open
ALTE05N1 Umbrella Long-term Follow-up Protocol Open