Skip to main content

8110 Gatehouse Road, Falls Church, VA 22042

SPHERE Uptravi® (SelexiPag): tHe usErs dRug rEgistry (SPHERE)


General Information

Age Group




Protocol Number


Background Information

To develop and maintain a database of de-identified patient medical information and other related information in order to better assess and optimize outcomes for patients diagnosed with PAH and receiving treatment with Uptravi®.

Age Group: Patients ≥ 18 years of age at time of Uptravi initiation.

National Clinical Trial (NCT) identifier on NCT03278002

Offered At

Inova Heart and Vascular Institute, Advanced Lung Disease and Transplant Clinic, 3300 Gallows Road, Falls Church, VA 22042

Principal Investigator

Oksana Shlobin, MD

Eligibility Information

Eligibility Information (brief)

  • Signed patient ICF.
  • Patients with PAH who either initiate Uptravi at the time of enrollment or have been receiving treatment with Uptravi and have a documented titration regimen (defined as all documented dose changes including, but not limited to: starting dose and highest tolerated dose).

Ineligibility Information

Ineligibility information (brief)

  • Patients previously exposed to Uptravi treatment during a clinical trial.