Contraindications

Absolute contraindications

Smoking. Patients should not be smoking for at least six months prior to placement on the list for transplantation.
Psychiatric disorders and psychosocial problems that are not resolved and will likely negatively impact the patient's outcome
Recent drug and/or alcohol abuse
Noncompliance with medical care or treatment plans even in the absence of documented psychiatric problems
Active malignancy within the past 2 years (except basal cell and squamous cell cancer of the skin) with a 5-year disease free interval for extracapsular renal cell tumors, breast cancer stage 2 or higher, colon cancer staged higher than Dukes A, and melanoma, level III or higher
A history of primary or metastatic lung malignancy
Ventilator dependency. Patients receiving non-invasive ventilation who meet all other criteria are candidates for lung transplantation.
Morbid obesity
Disabling arthritis or other condition limiting exercise
Progressive neuromuscular disorders
Systemic disease such as:
- Renal (creatinine clearance <50/mls/min)
- Liver disease (cirrhosis, chronic active, chronic persistent hepatitis, Hepatitis B, Hepatitis C with advanced or active disease)
- Insulin-dependent diabetes mellitus, which is not well-controlled or has resulted in any end-organ dysfunction
- Chronic pancreatitis
- Active connective tissue disorder

Relative contraindications

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Jane Harrison is recognized as a "Hero" by the Society of Transplant Social Workers.