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Indications

A patient may be considered for lung transplantation if he or she presents with end-stage lung disease from any of the conditions listed below and meets the age criteria.

Age criteria
  • Younger than 65 to 70 for a single lung transplant
  • Younger than 60 for a bilateral lung transplant
  • Younger than 55 for a heart-lung transplant

Other criteria
  • Conventional treatment has failed
  • Life expectancy is limited (less than 2-3 years)
  • Patient is at least ambulatory with oxygen to increase odds of a successful outcome
  • Patient meets the social and psychological profile to adhere to a disciplined medical regimen
  • Patient is willing to live less than 1 hour drive time from Inova Fairfax Hospital for at least several weeks following discharge from the hospital and 4 hours drive time from Inova Fairfax Hospital for at least 3 months following discharge from the hospital

Indications for single lung transplantation
  • Chronic obstructive pulmonary disease
  • Alpha-1 antitrypsin deficiency-induced emphysema
  • Pulmonary fibrosis of any cause
  • Sarcoidosis
  • Pulmonary langerhans cell histiocytosis (eosinophilic granuloma)
  • Lymphangioleiomyomatosis (LAM)
  • Bronchiolitis obliterans
  • Select patients with idiopathic pulmonary arterial hypertension (formerly known as primary pulmonary hypertension)/Eisenmenger's syndrome

Indications for bilateral lung transplantation
  • Cystic fibrosis
  • Select COPD patients (e.g., young age)
  • Select sarcoidosis patients
  • Bronchiectasis
  • Most patients with idiopathic pulmonary arterial hypertension/Eisenmenger's syndrome

Indications for heart-lung transplantation
  • Eisenmenger's syndrome with irreparable cardiac defect(s) or irreversible cardiac failure
  • Sarcoidosis with significant cardiac involvement